From Route 6:

Take exit 10 and proceed south on Route 124.  In approximately 1.5miles you will come to a stop sign in Harwich Center.  Make a right turn, proceed straight, west.  This is the beginning of Great Western Road. Now, follow directions from Harwich Center…

From Harwich Center:

Proceed directly west towards Dennis on Great Western Road.  In approximately 1/2 mile, take the first primary right turn onto Main Street.  Go past Station Avenue on the left, then go approximately 200 yards more and enter Olde Depot Industrial Park (527 Main Street) on the left.  First Crush Winey resides in buildings 16-18.  Enter at #18.

From Dennis:

From the traffic light at the intersection of Route 134 and Upper County Road, proceed east onto Upper County and take an immediate left onto Great Western Road. Proceed approximately 2.5 miles, past Depot Street, past the bike-path crossing, and take the next left onto Lothrop. Go to the end of Lothrop and take a right onto Main Street. Proceed approximately 1/3 mile and the road will have two S-turns. Immediately after the S-turns in the road, take a right into Olde Depot Industrial Park, 527 Main Street. First Crush Winery resides in buildings 16, 17 and 18. Enter at #18.